How effective and safe are drugs for the management of cancer related fatigue (CRF)?
It was not possible to determine optimum doses as a result of this review. Although haemopoietic growth factors and psychostimulants may be effective in treating CRF, they can have serious side effects (convulsions and thrombo-embolic events with erythropoietin and darbopoietin and convulsions, tachycardia and blood dyscrasias with methylphenidate). They should be used under expert supervision and their effects closely monitored.
CRF is common, under-recognised, and difficult to treat. It can occur as a side effect of treatment or because of the disease itself, and can have a significant impact on quality of life and a person’s ability to function.