How effective are homemade spacers (plastic cold-drink bottles, polystyrene cups, plastic zip-up bags) in delivering bronchodilator therapy to children with acute exacerbations of wheezing or asthma?
Care should be taken in the interpretation and applicability of these results because of the small number of randomised controlled trials, along with few events available meeting the criteria for inclusion in the review, and absence of the primary outcome of interest and other clinically important outcomes in the majority of the included studies. Given the small total sample and wide confidence intervals, equivalence between the treatments cannot be claimed.
Asthma is a major cause of childhood morbidity¹ and disability² with acute exacerbations of the disease being a common reason for emergency department admissions and hospital admissions.³ Inhaled therapy using a MDI with attached spacer, has been increasingly recognised as the optimal method of delivering rapid acting beta 2 agonists for acute exacerbation of wheezing or asthma. 1. Braman SS. Chest 2006;130:4S-12S. 2. Newacheck PW et al. Archives of Paediatric and Adolescent Medicine 2000;154:287-293. 3. Akinbami LJ et al. Paediatrics 2002; 110:315-322.