How effective are angiotensin converting enzyme (ACE) inhibitors in lowering blood pressure (BP) in primary hypertension?
Due to lack of reporting and the short duration of these trials (3 to 12 weeks), this review did not provide a good estimate of the harms associated with this class of drugs.
ACE inhibitors are commonly used for the treatment of elevated blood pressure. This class includes drugs such as ramipril, captopril, enalapril, fosinopril, lisinopril and quinapril. Despite over 20 years of research evidence and clinical use of ACE inhibitors, the dose-related BP lowering effect of this antihypertensive drug class is still not known.