How effective are alpha blockers in the treatment of primary hypertension?
Given the high likelihood of publication bias, the estimates of BP lowering effect calculated are likely to be an overestimate of the real effect. The effect of alpha blockers on BP variability, pulse pressure, or heart rate could not be determined.
Alpha blockers are used as pharmacological agents for the treatment of hypertension. Despite nearly 30 years of research evidence and clinical use of alpha blockers, the dose-related BP lowering effect of this antihypertensive drug class is still not known.