How effective are the different classes of antibiotics given as prophylaxis for infection prior to caesarean section (CS)?
There was a lack of good quality data, and important outcomes often included only small numbers of women. Many of the studies were conducted in the 1980s and 1990s. None of the studies assessed infections that arose when the women were discharged home, and none looked at outcomes in the babies. No consideration was given to antibiotics compatible with breastfeeding, and the review was unable to assess what impact, if any, the use of different types of antibiotics might have had on bacterial resistance.
CS increases the risk of post-partum infection (infections of the wound or abdominal fascia, the urinary tract or pelvic organs, as well as thrombophlebitis and, rarely, septicaemia), and prophylactic antibiotics have been shown to reduce the incidence of this.