How effective are cranberry products in preventing urinary tract infections (UTIs) in susceptible populations?
Many people in the trials stopped drinking the juice, suggesting it may not be a popular intervention. It is not clear how long cranberry juice needs to be taken to be effective or what the required dose might be.
No definite mechanism of action has been established for cranberries in the prevention or treatment of UTI. However, the main suggestion is cranberries prevent bacteria, particularly Escherichia coli, from adhering to uroepithelial cells lining the bladder. Without adhesion, E. coli cannot infect the mucosal surface of the urinary tract.