How effective are interventions for post-stroke fatigue?
There were only 3 completed studies, providing data on a total of 226 patients, and these involved 3 different interventions. There were methodological limitations with all 3 trials. It was not possible to perform meta-analysis as the interventions were too dissimilar.
Estimates of the prevalence of fatigue after stroke range from 16%¹ to 70%,²,³ depending on the population studied (eg, inpatients or community patients, time since stroke, severity of stroke), whether people with depression were included or excluded, and how fatigue was identified (eg, single question or fatigue scales). 1. Glader E-L et al. Stroke 2002;33:1327-33. 2. Carllson GE et al. Cerebrovasc Dis 2003;16:383-88. 3. Leegard OF. Acta Neurol Scand 1983;67:348-55.