How effective are statins in delaying the onset and/or progression of age-related macular degeneration (AMD)?
There were only 2 small studies, one of which is still ongoing.
AMD is a progressive late onset disorder of the macula that affects central vision. Although AMD is the leading cause of blindness in people over 65 years in industrialised countries,¹ its pathogenesis is not clearly understood. Recent epidemiologic, genetic and pathological evidence has shown AMD shares a number of risk factors with atherosclerosis, leading to the hypothesis that statins may exert protective effects in AMD. 1. Congdon NG et al. JAMA 2003;290:2057-60