How effective is early treatment with statins in patients with acute coronary syndrome (ACS)?
In most of the landmark trials of statins in patients with chronic coronary heart disease (CHD), a benefit of treatment was not evident until 1–2 years after randomisation. Therefore, some of the benefit of statin treatment in the period up to 4 months after ACS may only become manifest after 4 months.
Long-term therapy with statins (for at least 1 year) has been shown to reduce the risk of heart attack, stroke and all-cause mortality in patients with and without established CHD. The early period following ACS is a critical stage of CHD, with a high risk of recurrent events and death. The effects of early treatment with statins in patients suffering from ACS are unclear.