How effective is percutaneous transluminal angioplasty (PTA) when compared with PTA and stenting for lesions of the superficial femoral artery (SFA), for people with intermittent claudication or critical limb ischaemia?
Protocols between trials varied, and the benefit may be limited to patients with SFA disease, subsequently treated with clopidogrel. In some trials, patients with narrowings in other leg arteries were included. There were also differences in the anticoagulants given after stent placement between trials, which may change results.
Lower limb peripheral arterial disease is a common, important manifestation of systemic atherosclerosis. It occurs in 3% to 10% of the population, increasing to 15% to 20% in people over 70 years of age.¹ Stenoses or occlusions in the SFA may result in intermittent claudication as an early consequence, which may be treated by balloon angioplasty, with or without stenting. 1. Selvin E, Erlinger TP. Circulation 2004;110:738-43