How effective are drug-eluting stents compared with bare metal stents in the reduction of cardiac events (angina or acute coronary syndrome)?
The review was unable to report outcomes uniformly across all-time points and for all outcomes for all drugs. Long-term efficacy and safety data have not yet been confirmed as few trials reported outcomes beyond one or two years.
Coronary artery stents are small, tubular devices used to “scaffold” vessels open during percutaneous transluminal coronary angioplasty. Restenosis of vessels treated with stents is a problem; in order to reduce restenosis, stents that elute drugs over time have been developed. However, there is a need to assess their clinical benefit prior to recommending their use. The increased cost of drug-eluting stents and current lack of evidence of their cost-effectiveness means that various health funding agencies are limiting or regulating their use.