How effective is omega-3 supplementation in people with intermittent claudication?
The studies were statistically and clinically heterogeneous in terms of dose, duration of therapy and placebo used. None of the studies used an inactive placebo. The duration of the studies ranged from 7 weeks to 2 years.
Omega-3 fatty acids have been used in the treatment and prevention of coronary artery disease although current evidence suggests they may be of limited benefit. Peripheral arterial disease and coronary artery disease share a similar pathogenesis, so omega-3 fatty acids may have a similar effect on both conditions.