What is the most effective duration of treatment for asymptomatic bacteriuria during pregnancy?
In general, the trials lacked evidence of sufficient rigour in the design, conduct and analysis of results. The poor methodological quality of these trials may obscure any important clinical and laboratory differences between duration of treatment regimens.
Asymptomatic bacteriuria is common in pregnancy. A Cochrane systematic review has shown drug treatment of asymptomatic bacteriuria in pregnant women substantially decreases the risk of pyelonephritis and reduces the risk of preterm delivery.1 However, it is not clear whether single-dose therapy is as effective as longer, conventional, antibiotic treatment.