How effective is magnesium sulphate for eclampsia?
Recruitment to trials in this review was primarily from hospitals in low- and middle-income countries, which is where 99% of maternal deaths occur. None of the trials were conducted at primary care level, and none included evaluation of care during transfer to a higher level of care.
Eclampsia is rare: in high-income countries it affects 2 to 3 in every 10,000 pregnant women, and in low- and middle-income countries 16 to 69 in every 10,000. However, 15% of maternal deaths are associated with eclampsia.