How effective are non-steroidal anti-inflammatory drugs (NSAIDs) in the treatment of primary dysmenorrhoea?
The included studies used a wide variety of continuous pain scales as their primary or sole measure of effectiveness. The measurement and reporting of adverse effects was generally poor. At least half the studies were co-authored or financially supported by pharmaceutical company associates and it was unclear how most of the other studies were funded.
Dysmenorrhoea is a common gynaecological problem, consisting of painful cramps accompanying menstruation, which in the absence of any underlying abnormality is known as primary dysmenorrhoea. Research has shown women with dysmenorrhoea have high levels of prostaglandins, hormones known to cause cramping abdominal pain. NSAIDs are drugs which act by blocking prostaglandin production.