Can I safely prescribe cardioselective beta-blockers for individuals with chronic obstructive pulmonary disease (COPD)?
The mean duration of the studies included in the meta-analysis was only 3.7 weeks (range 2 days to 12 weeks). Most of the studies were small.
Beta-blocker therapy has a proven mortality benefit in patients with hypertension, heart failure and coronary heart disease. Traditionally these drugs have been considered contraindicated in patients with COPD.